Hex style nuts allow wrench tightening; however, since they are polymeric, they can break and are recommended for use only when space is limited and fingers won't fit.
PEEK nuts are intended for use only with polymeric ferrules, which seal with lower force than their stainless steel counterparts. Overtightening can result in breakage.
MORE INFORMATION
TechNote 503: Fitting Instructions
Properties of Polymers: PEEK
Dimensional Drawings